[Ozurdex(®) and aphakia: a combination to avoid].
نویسندگان
چکیده
zurdex® (Allergan Inc., Irvine, CA, USA) is a biodegradable mplant for the sustained release of intravitreal dexamethaone which has recently been approved as a treatment for acular edema secondary to retinal venous occlusion and n posterior uveitis of non-infectious cause.1 Ozurdex® has lso demonstrated its efficiency in diabetic and pseudophakic acular edema. Before it was placed on the market, Ozurdex® was not dministered to aphakic patients. The technical data of the rug do not consider complications in this group of patients nd literally state that “Ozurdex must be used with caution in phakic patients”. Pardo-López et al.2 described the first case of implant igration to the anterior chamber (AC) in a patient with ntraocular lens fixed to the iris and intra-surgery capsular upture. The implant was removed surgically but the patient equired corneal transplant. Bansal et al.3 published 3 cases f implant migration to AC, all in patients with noninfecious posterior uveitis and post-vitrectomy and lensectomy phakia. In 2 of the cases, the implant was relocated in the itreous cavity and the third required surgical removal with ost surgery persistence of corneal edema.
منابع مشابه
Wandering Ozurdex® implant
PURPOSE To report the behavior of intravitreal Ozurdex(®) implant in eyes with post-lensectomy-vitrectomy (PLV) aphakia. METHODS Retrospective chart review of three eyes with PLV aphakia (three patients with uveitis) who received intravitreal injection of Ozurdex(®) for cystoid macular edema (one eye), persistent inflammation (one eye), and ocular hypotony (one eye). Final outcome was assesse...
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BACKGROUND Ozurdex is a 700 mcg dexamethasone intravitreal implant, approved for the management of macular edema secondary to retinal vein occlusion, and other related pathoglogiesAnterior chamber dislocation of Ozurdex represents an uncommon complication of the intravitreal injection, which can be managed by repositioning the implant into the vitreous cavity. We describe the case of a successf...
متن کاملA prospective randomised controlled clinical trial comparing a combination of repeated intravitreal Ozurdex and macular laser therapy versus macular laser only in centre-involving diabetic macular oedema (OZLASE study).
BACKGROUND/AIMS To evaluate the clinical efficacy and safety of combined repeated Ozurdex and macular laser therapy (MLT) compared with MLT monotherapy in participants with visual impairment due to centre-involving diabetic macular oedema (DMO). METHODS 80 patients with best corrected visual acuity (BCVA) between 54 and 78 ETDRS letters due to centre-involving DMO were randomised to combinati...
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A 58-year-old man admitted to our opthalmology department with the complaint of branch retinal vein occlusion. He was treated with intravitreal Ozurdex in the right eye. Two days after the injection, the patient presented with ocular pain and the visual acuity was hand movement. A diagnosis of endophthalmitis was made. We performed emergent pars plana vitrectomy (PPV) and the implant was remove...
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A 65-year-old female presented with visual disturbance in her right eye lasting for over 2 months. Following investigations, she was diagnosed with MacTel type 1 in the right eye. Visual symptoms were refractory to initial treatment with intravitreal bevacizumab and thereafter intravtireal triamicinolone. The patient was then treated with Ozurdex, following which central macular thickness (CMT)...
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ورودعنوان ژورنال:
- Archivos de la Sociedad Espanola de Oftalmologia
دوره 87 6 شماره
صفحات -
تاریخ انتشار 2012